黄福建 教授 硕士生导师

中国地质大学（武汉） 材料与化学学院

湖北省武汉市东湖新技术开发区锦程街68号 材化楼524室

Email：huangfj@cug.edu.cn

教育与研究经历

2016年7月——至今          中国地质大学（武汉）材料与化学学院  教授

2015年6月——2016年6月    以色列希伯来大学化学系              博士后研究员

（合作导师：Itamar Willner 教授）

2013年6月——2015年5月   中国科学技术大学高分子科学与工程系   博士后研究员

（合作导师：梁好均教授）

2011年9月——2012年9月   美国佛罗里达大学化学系               联合培养博士

（导师：谭蔚泓院士）

2007年9月——2013年6月   中国科学技术大学                     理学博士

2003年9月——2007年7月   合肥工业大学                         工学学士

学术成果

目前主要从事的研究领域包括响应性核酸器件、单细胞分析检测以及光响应DNA水凝胶等。迄今为止，在功能性核酸器件的构建、光响应核酸器件的制备及应用等方面取得了一系列的成果。提出了光控DNA链替换反应及光控DNA杂交链增长反应，构建了光控的DNA微胶囊可控载药体系，建立了基于光控DNA链替换反应及光控DNA杂交链增长反应的表面多色及可擦写DNA光刻新技术。已在J. Am. Chem. Soc. （2篇），ACS Nano （1篇），Small （1篇），Chem. Commun. （2篇），Nanoscale （1篇）等国际期刊上发表SCI论文27篇。SCI引用300余次，H因子11。

承担项目与课题

1. 颗粒表面不对称DNA修饰及可控自组装研究（国家自然科学基金青年基金）

2. 多色及可擦写DNA光刻研究（博士后面上基金）

3. 多色及可擦写DNA光刻研究（中央高校基本科研基金）

代表性成果

1.  Bei Wang, Xiaojing Wang, Bing Wei, Fujian Huang*, Dongbao Yao, Haojun Liang*; “DNA photonic nanowires with tunable FRET signals on the basis of toehold-mediated DNA strand displacement reactions”. Nanoscale, 2017, 9, 2981-2985. (IF= 7.760)

2. Fujian Huang, Wei-Ching Liao, Yang Sung Sohn, Rachel Nechushtai, Chun-Hua Lu, Itamar Willner*; "Light-Responsive and pH-Responsive DNA Microcapsules for Controlled Release of Loads ". Journal of the American Chemical Society, 2016, 138, 8936-8945. (IF= 13.038)

3. Fujian Huang, Xiang Zhou, Dongbao Yao, Shiyan Xiao, Haojun Liang*; "DNA Polymer Brush Patterning through Photocontrollable Surface‐Initiated DNA Hybridization Chain Reaction". Small, 2015, 11, 5800-5806. (IF= 8.315)

4.  Fujian Huang, Huaguo Xu, Weihong Tan*, Haojun Liang*; "Multicolor and erasable DNA photolithography". ACS nano, 2014, 8, 6849-6855. (IF= 13.334)

5.  Fujian Huang, Pingping Xu, Haojun Liang*; "Using dual-polarization interferometry to study surface-initiated DNA hybridization chain reactions in real time". Biosensors and Bioelectronics, 2014, 51, 317-323. (IF= 7.467)

6.  Fujian Huang, Mingxu You, Tao Chen, Guizhi Zhu, Haojun Liang*, Weihong Tan*; "Self-assembled hybrid nanoparticles for targeted co-delivery of two drugs into cancer cells". Chemical Communications, 2014, 50, 3103-3105. (IF= 6.567)

7.  Huaguo Xu, Wei Deng, Fujian Huang*, Shiyan Xiao, Gang Liu, Haojun Liang*; "Enhanced DNA toehold exchange reaction on a chip surface to discriminate single-base changes". Chemical Communications, 2014, 50, 14171-14174. (IF= 6.567)

8.  Huaguo Xu, Fujian Huang*, Haojun Liang*; "Adsorption of Polyethylenimine and Its Interaction with a Genomic DNA on Silicon Oxynitride Surface Characterized by Dual Polarization Interferometry". RSC Advances, 2014, 4, 44700-44705. (IF= 3.289)

9.  Fujian Huang, Mingxu You, Da Han, Xiangling Xiong, Haojun Liang*, Weihong Tan*; "DNA branch migration reactions through photocontrollable toehold formation". Journal of the American Chemical Society, 2013, 135, 7967-7973. (IF= 13.038)

10.  Fujian Huang, Haojun Liang; "Adsorption Behaviors of DNA/Cation Complexes on Amino and Silica Chip Surfaces: A Dual Polarization Interferometry Study". ACS Applied Materials & Interfaces, 2013, 5, 5025-5033. (IF= 7.145)

11.  Xuehong Min, Mengshi Zhang, Fujian Huang, Xiaoding Lou*, and Fan Xia; "Live Cell MicroRNA Imaging Using Exonuclease III-Aided Recycling Amplification Based on Aggregation-Induced Emission Luminogens". ACS Applied Materials & Interfaces, 2016, 8, 8998-9003. (IF= 7.145)

12.  Yuan Zhuang, Fujian Huang, Qi Xu, Mengshi Zhang, Xiaoding Lou*, and Fan Xia; "Facile, Fast-Responsive, and Photostable Imaging of Telomerase Activity in Living Cells with a Fluorescence Turn-On Manner". Analytical Chemistry, 2016, 88, 3289-3294. (IF= 5.886)

13.  Dongbao Yao, Tingjie Song, Xianbao Sun, Shiyan Xiao*, Fujian Huang, and Haojun Liang*; "Integrating DNA-Strand-Displacement Circuitry with Self-Assembly of Spherical Nucleic Acids". Journal of the American Chemical Society, 2015, 137, 14107-14113. (IF= 13.038)

14.  Dongbao Yao, Tingjie Song, Bin Zheng, Shiyan Xiao, Fujian Huang and Haojun Liang*; "The combination of gold nanorods and nanoparticles with DNA nanodevices for logic gates construction". Nanotechnology, 2015, 26, 425601. (IF= 3.573)

15.  Dongbao Yao, Bei Wang, Shiyan Xiao*, Tingjie Song, Fujian Huang, and Haojun Liang*; "What Controls the “Off/On Switch” in the Toehold-Mediated Strand Displacement Reaction on DNA Conjugated Gold Nanoparticles?" Langmuir, 2015, 31, 7055-7061. (IF= 3.993)

16.  Jing Jin, Fujian Huang, Yu Hu, Wei Jiang, Xiangling Ji, Haojun Liang, Jinghua Yin; “Immobilizing PEO–PPO–PEO triblock copolymers on hydrophobic surfaces and its effect on protein and platelet: A combined study using QCM-D and DPI”. Colloids and Surfaces B: Biointerfaces, 2014, 123, 892-899. (IF= 3.902)

17.  Tingjie Song, Shiyan Xiao, Dongbao Yao, Fujian Huang, Maobin Hu, Haojun Liang*; “An Efficient DNA‐Fueled Molecular Machine for the Discrimination of Single‐Base Changes”. Advanced Materials, 2014, 26, 6181-6185. (IF= 18.96)

18.  Pingping Xu, Fujian Huang, Haojun Liang*; “Real-time study of a DNA strand displacement reaction using dual polarization interferometry”. Biosensors and Bioelectronics, 2013, 41, 505-510. (IF= 7.467)

19.  Mingxu You, Fujian Huang, Zhuo Chen, Ruo-Wen Wang, Weihong Tan*; “Building a nanostructure with reversible motions using photonic energy”. ACS nano, 2012, 6, 7935-7941. (IF= 13.334)