黄福建 教授 硕士生导师
中国地质大学(武汉) 材料与化学学院
湖北省武汉市东湖新技术开发区锦程街68号 材化楼524室
Email:huangfj@cug.edu.cn
教育与研究经历
2016年7月——至今 中国地质大学(武汉)材料与化学学院 教授
2015年6月——2016年6月 以色列希伯来大学化学系 博士后研究员
(合作导师:Itamar Willner 教授)
2013年6月——2015年5月 中国科学技术大学高分子科学与工程系 博士后研究员
(合作导师:梁好均教授)
2011年9月——2012年9月 美国佛罗里达大学化学系 联合培养博士
(导师:谭蔚泓院士)
2007年9月——2013年6月 中国科学技术大学 理学博士
2003年9月——2007年7月 合肥工业大学 工学学士
学术成果
目前主要从事的研究领域包括响应性核酸器件、单细胞分析检测以及光响应DNA水凝胶等。迄今为止,在功能性核酸器件的构建、光响应核酸器件的制备及应用等方面取得了一系列的成果。提出了光控DNA链替换反应及光控DNA杂交链增长反应,构建了光控的DNA微胶囊可控载药体系,建立了基于光控DNA链替换反应及光控DNA杂交链增长反应的表面多色及可擦写DNA光刻新技术。已在J. Am. Chem. Soc. (2篇),ACS Nano (1篇),Small (1篇),Chem. Commun. (2篇),Nanoscale (1篇)等国际期刊上发表SCI论文27篇。SCI引用300余次,H因子11。
承担项目与课题
1. 颗粒表面不对称DNA修饰及可控自组装研究(国家自然科学基金青年基金)
2. 多色及可擦写DNA光刻研究(博士后面上基金)
3. 多色及可擦写DNA光刻研究(中央高校基本科研基金)
代表性成果
1. Bei Wang, Xiaojing Wang, Bing Wei, Fujian Huang*, Dongbao Yao, Haojun Liang*; “DNA photonic nanowires with tunable FRET signals on the basis of toehold-mediated DNA strand displacement reactions”. Nanoscale, 2017, 9, 2981-2985. (IF= 7.760)
2. Fujian Huang, Wei-Ching Liao, Yang Sung Sohn, Rachel Nechushtai, Chun-Hua Lu, Itamar Willner*; "Light-Responsive and pH-Responsive DNA Microcapsules for Controlled Release of Loads ". Journal of the American Chemical Society, 2016, 138, 8936-8945. (IF= 13.038)
3. Fujian Huang, Xiang Zhou, Dongbao Yao, Shiyan Xiao, Haojun Liang*; "DNA Polymer Brush Patterning through Photocontrollable Surface‐Initiated DNA Hybridization Chain Reaction". Small, 2015, 11, 5800-5806. (IF= 8.315)
4. Fujian Huang, Huaguo Xu, Weihong Tan*, Haojun Liang*; "Multicolor and erasable DNA photolithography". ACS nano, 2014, 8, 6849-6855. (IF= 13.334)
5. Fujian Huang, Pingping Xu, Haojun Liang*; "Using dual-polarization interferometry to study surface-initiated DNA hybridization chain reactions in real time". Biosensors and Bioelectronics, 2014, 51, 317-323. (IF= 7.467)
6. Fujian Huang, Mingxu You, Tao Chen, Guizhi Zhu, Haojun Liang*, Weihong Tan*; "Self-assembled hybrid nanoparticles for targeted co-delivery of two drugs into cancer cells". Chemical Communications, 2014, 50, 3103-3105. (IF= 6.567)
7. Huaguo Xu, Wei Deng, Fujian Huang*, Shiyan Xiao, Gang Liu, Haojun Liang*; "Enhanced DNA toehold exchange reaction on a chip surface to discriminate single-base changes". Chemical Communications, 2014, 50, 14171-14174. (IF= 6.567)
8. Huaguo Xu, Fujian Huang*, Haojun Liang*; "Adsorption of Polyethylenimine and Its Interaction with a Genomic DNA on Silicon Oxynitride Surface Characterized by Dual Polarization Interferometry". RSC Advances, 2014, 4, 44700-44705. (IF= 3.289)
9. Fujian Huang, Mingxu You, Da Han, Xiangling Xiong, Haojun Liang*, Weihong Tan*; "DNA branch migration reactions through photocontrollable toehold formation". Journal of the American Chemical Society, 2013, 135, 7967-7973. (IF= 13.038)
10. Fujian Huang, Haojun Liang; "Adsorption Behaviors of DNA/Cation Complexes on Amino and Silica Chip Surfaces: A Dual Polarization Interferometry Study". ACS Applied Materials & Interfaces, 2013, 5, 5025-5033. (IF= 7.145)
11. Xuehong Min, Mengshi Zhang, Fujian Huang, Xiaoding Lou*, and Fan Xia; "Live Cell MicroRNA Imaging Using Exonuclease III-Aided Recycling Amplification Based on Aggregation-Induced Emission Luminogens". ACS Applied Materials & Interfaces, 2016, 8, 8998-9003. (IF= 7.145)
12. Yuan Zhuang, Fujian Huang, Qi Xu, Mengshi Zhang, Xiaoding Lou*, and Fan Xia; "Facile, Fast-Responsive, and Photostable Imaging of Telomerase Activity in Living Cells with a Fluorescence Turn-On Manner". Analytical Chemistry, 2016, 88, 3289-3294. (IF= 5.886)
13. Dongbao Yao, Tingjie Song, Xianbao Sun, Shiyan Xiao*, Fujian Huang, and Haojun Liang*; "Integrating DNA-Strand-Displacement Circuitry with Self-Assembly of Spherical Nucleic Acids". Journal of the American Chemical Society, 2015, 137, 14107-14113. (IF= 13.038)
14. Dongbao Yao, Tingjie Song, Bin Zheng, Shiyan Xiao, Fujian Huang and Haojun Liang*; "The combination of gold nanorods and nanoparticles with DNA nanodevices for logic gates construction". Nanotechnology, 2015, 26, 425601. (IF= 3.573)
15. Dongbao Yao, Bei Wang, Shiyan Xiao*, Tingjie Song, Fujian Huang, and Haojun Liang*; "What Controls the “Off/On Switch” in the Toehold-Mediated Strand Displacement Reaction on DNA Conjugated Gold Nanoparticles?" Langmuir, 2015, 31, 7055-7061. (IF= 3.993)
16. Jing Jin, Fujian Huang, Yu Hu, Wei Jiang, Xiangling Ji, Haojun Liang, Jinghua Yin; “Immobilizing PEO–PPO–PEO triblock copolymers on hydrophobic surfaces and its effect on protein and platelet: A combined study using QCM-D and DPI”. Colloids and Surfaces B: Biointerfaces, 2014, 123, 892-899. (IF= 3.902)
17. Tingjie Song, Shiyan Xiao, Dongbao Yao, Fujian Huang, Maobin Hu, Haojun Liang*; “An Efficient DNA‐Fueled Molecular Machine for the Discrimination of Single‐Base Changes”. Advanced Materials, 2014, 26, 6181-6185. (IF= 18.96)
18. Pingping Xu, Fujian Huang, Haojun Liang*; “Real-time study of a DNA strand displacement reaction using dual polarization interferometry”. Biosensors and Bioelectronics, 2013, 41, 505-510. (IF= 7.467)
19. Mingxu You, Fujian Huang, Zhuo Chen, Ruo-Wen Wang, Weihong Tan*; “Building a nanostructure with reversible motions using photonic energy”. ACS nano, 2012, 6, 7935-7941. (IF= 13.334)